SFI Health

Panax ginseng (G115®)

Natural energiser

Panax ginseng is used in Ginsana to support energy levels and physical endurance

Panax ginseng is a highly valued plant traditionally used in Chinese medicine, and today to support energy levels and physical endurance.

 

In Ginsana®, a specific standardised extract from the roots of Panax ginseng C.A. Meyer called G115 is used.

 

Discover more about the unique G115 extract used by SFI Health, how it works, and the key studies that support its benefits when used in Ginsana.

Panax ginseng in history

Panax ginseng is a perennial shrub, native to north-eastern China, Korea and Russia.1 It was traditionally used as a tonic to support the body in times of increased demand and to promote good health and vitality.2-4

Panax ginseng was first recorded in Chinese medicine over 2000 years ago, and was already the subject of over 600 published books and papers before the year 2000.2,5

 

You may have heard of ‘ginseng’ before, but it’s important to know that not all ginseng is the same. Ginseng comprises a genus called ‘Panax. Several species of ginseng exist within this, e.g. Panax ginseng CA Meyer, Panax notoginseng and so on.  All are ginseng - but there is one with far more clinical research supporting its medical use. This is Panax ginseng CA Meyer.

 

The herb’s name comes from Panax meaning ‘cure all’ in Greek and ginseng from the Chinese (Mandarin) rén shn meaning ‘man ginseng’ because of the human like shape of the plant’s root.6

Panax ginseng in history

The specific extract used by SFI Health: G115

G115 is the specific extract of Panax ginseng used by SFI Health in Ginsana. Its first mention goes back to 1960, and it has over 35 years of research supporting it.7

The special extract G115 is produced from the roots of Panax ginseng C.A. Meyer. This is where most of the important ingredients lie, including the active ingredient – the ‘ginsenosides’. It takes up to five years, and involves multiple steps for a Panax ginseng root to become G115, ensuring that there is an optimal concentration of the active therapeutic components.

 

Thanks to a complex process, the G115 extract in Ginsana, contains a consistent content of ginsenosides - 4% to be exact. Because all G115 extract has the same concentration of active ingredient, it is possible to accurately investigate its safety and effectiveness in clinical trials. 

 

The beneficial effect of G115 is based on numerous clinical trials in humans. Results from these clinical studies suggests that G115 may:8-16,17-20

 

  • Enhance physical capacities in the case of weakness and fatigue
  • Increase endurance time
  • Shorten recovery time
The specific extract used by SFI Health: G115

How G115 works

G115 belongs to the so called ’adaptogenic’ substances. In times of stress, and decreased physical performance, adaptogenic substances increase the capability of the body to overcome adverse external influences.

G115 is known to:21-34

  • Influence energy utilization in the muscles – helping to increase endurance
  • Increase oxygen uptake – helping to reduce fatigue
  • Act on the central nervous system – reducing stress, physical and mental tension
  • Act on the immune system – promoting immune function

Preclinical studies have also demonstrated that G115 is able to increase Adenosine Triphosphate (ATP), the molecule that provides energy to all cells in the body.21,22

How G115 works

G115 in clinical trials

More than 30 clinical studies, involving more than 1000 participants1, have been conducted with G115 over the last 35 years demonstrating the benefits of the unique extract, while generally well tolerated with no serious adverse events reported.

Gundling 200244

175 volunteers

8 weeks*

IMPROVEMENT

vs. placebo for patients taking Ginsana:

  • Improved immune response
    Provided additional protection against infleunza and common cold
    Enhanced levels of antibodies against influenza

* 2 treatment groups; 2 Ginsana capsules daily (100 mg G115) or placebo

Scaglione 200143

75 patients with acute attacks of chronic bronchitis

9 days*

SIGNIFICANT IMPROVEMENT

for patients taking Ginsana:

  • Faster bacterial clearance

* 2 treatment groups; 1 Ginsana capsule daily (100 mg G115) plus antibacterial treatment or antibacterial treatment only.

All patients received amoxicillin and clavulanic acid.

Scaglione 199642

227 volunteers

12 weeks*

SIGNIFICANT IMPROVEMENT

vs. placebo for patients taking Ginsana:

  • Proportion of volunteers who caught influenza was lower
    Level of antibodies to influenza was increased
    Additional protection against influenza and common cold

* 2 treatment groups; 2 Ginsana capsules twice daily (100 mg G115) or placebo. After 4 weeks participants received an anti-influenza vaccination

Scaglione 199441

40 smoking volunteers

8 weeks*

IMPROVEMENT

vs. placebo for patients taking Ginsana:

  • Immune response (related to lung alveolar)

*2 treatment groups; 1 Ginsana capsule every 12 hours (100 mg G115) or placebo

Scaglione 199040

60 healthy adults

8 weeks*

SIGNIFICANT IMPROVEMENT

vs. placebo for patients taking Ginsana or aqueous ginseng extract:

  • stimulated immune responses
    G115 positively influenced the variety of immune cells

*3 treatment groups; 1 Ginsana capsule every 12 hours containing either 100 mg G115 extract or 100mg aqueous ginseng extract or placebo

von Schepdael 199316

43 triathlon athletes

10 weeks

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • physical endurance
    oxygen uptake
Forgo & Schimert 198515

28 male athletes

9 weeks

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • recovery time
    oxygen uptake
    lung function
    heart rate
Forgo & Kirchdorfer 198214

30 top class athletes

9 weeks

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • physical work capacity
    recovery time
    oxygen absorption
    lactate levels
    heart rate
Forgo 198313

30 top sportsmen

9 weeks

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • fitness
    recovery time
    oxygen absorption
    lactate levels
    heart rate
Forgo & Kirchdorfer 198112

20 top sportsmen

9 weeks

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • recovery time
    physical performance
    oxygen uptake
    lactate levels
    heart rate
Forgo 198111

120 healthy adults

3 days*

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • Physical function
    Mental function
Dorling 198010

60 healthy adults

90 days

POSITIVE EFFECT

  • Subjective physical condition
    Physical fitness
    Sleep behaviour
Gianoli 19849

87 patients with fatigue

2 months

SIGNIFICANT IMPROVEMENT

vs. placebo for:

  • Performance
    Energy
    Wellbeing
    Fatigue and exhaustion
Rosenfeld 19898

50 patients with fatigue and neurological disorders

56 days

SIGNIFICANT IMPROVEMENT

for:

  • Tiredness (subjective questionnaire)

SFI Health Difference

What makes Ginsana different?

 

Natural medicines can vary considerably depending on the species of plant chosen, the way they are grown and harvested, and the extraction and production process. Therefore, it’s essential to ensure the active ingredient in your product is the same type, and in the same quantity, as the one used in clinical trials.

 

In Ginsana, we take care to use the same specific extract (G115®) that's been proven in clinical studies to help support energy and endurance. That’s why you can be confident that Ginsana offers the same benefits as demonstrated in the clinical trials.

G115: A Summary

>35 YEARS OF RESEARCH

Numerous preclinical and clinical studies investigating the beneficial effect Panax ginseng.1

>30 CLINICAL TRIALS

 Support the role of G115 in enhancing energy and endurance levels.

CONSISTENT QUALITY

Through our rigorous processes, quality controls and extensive testing we ensure that the G115 extract provides the desired health outcomes demonstrated by clinical trials.

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