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Equazen® Forte
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The role of essential fatty acids (EFAs), which include omega-3s (EPA and DHA) and omega-6 (GLA), to support healthy brain function and learning development continues to grow as an area of research.

EQUAZENTM is made with a scientifically developed ratio of EPA:DHA:GLA (9:3:1), which has been shown in multiple clinical trials to support concentration, learning and reading.

Discover more about the clinically researched combination used in EQUAZENTM and the key studies that support its benefits.

Essential Fatty Acids in history

Dietary fats are part of our everyday diet. They belong to a larger group of compounds called lipids. Lipids help build our cell membranes and are vital to our central nervous system – making up about 50-60% of the weight of our brain.5

More on Essential Fatty Acids in history

Of these brain lipids, approximately 35% are made up of polyunsaturated fatty acids (PUFAs), which include the omega-3 essential fatty acids, EPA and DHA and omega-6 essential fatty acid, GLA. 5

These essential fatty acids (EFAs) are PUFAs that may not be made or stored by your body and it is therefore recommended to be provided through our diet.6  Over the years, fish oil has been recognised as a rich and important source of omega-3s (EPA and DHA) while evening primrose oil contains a natural source of omega-6 (GLA).

These EFAs are known to play important biological roles, being structural and functional components of cell membranes and research suggests they have a profound influence in the development of the central nervous system, brain and neuronal function. 6

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The optimal combination used in EQUAZENTM

EQUAZENTM  was developed based on years of research and expertise to provide an optimal balance of fish oil rich in omega-3s (EPA & DHA) and evening primrose oil rich in omega-6 (GLA). This combination is referred to as the Equabalance ratio EPA:DHA:GLA that is 9:3:1.

More on the optimal combination used in EQUAZEN

This optimal balance of EPA : DHA : GLA has been researched in 12 clinical studies.1-4, 7-14  

Evidence shows EQUAZENTM can help support:1-2

  • Concentration/attention
  • Learning
  • Reading
  • Language development
  • Working memory

Always read the label. Use only as directed. If symptoms persist consult your healthcare professional. Use in children under 3 is not recommended.

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Research on how essential fatty acids work

The essential fatty acids EPA, DHA and GLA have long been recognised for their role in the structure and function of cell membranes, anti-inflammatory processes in the body and growing research shows they can play an important role in supporting healthy brain function and development. 6

More on how essential fatty acids can work

The pre-clinical for essential fatty acids suggests they can help support:

  • Cell membrane structure, function and communication (including neuron cells)15-16
  • Nervous system function and development 15-16
  • Anti-inflammatory effects 15-16
  • Processes the can  play a role in healthy neuronal function  17-18
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Clinical studies on EQUAZENTM

EQUAZENTM   has been researched in multiple clinical studies involving both mainly children and also adults.  The evidence demonstrates the beneficial effects of the Equabalance ratio of EPA:DHA:GLA = 9:3:1  used in the EQUAZENTM  range, with significant improvement in concentration and learning development.

Stough 2001
154 children over 3 months
Significant Improvement

vs. placebo for performed tasks reflecting:

  • Concentration and attention
  • Learning and language
    development including reading
    and visual analysis
  • Working memory

Johnson et al. Child Psychol Psychiatry. 2017 Jan;58(1):83-93.

Parletta et al. 2013
409 children over 40 weeks
Significant Improvement

vs. placebo for performed tasks reflecting:

  • cognitive and learning
    development
  • Concentration and attention
  • Working memory

Parletta et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Aug;89(2-3):71-9.

Sinn et al. 2008
167 children over 30 weeks
Significant Improvement

vs. placebo for performed tasks reflecting:

  • Concentration and attention
  • Learning and language
    development

Sinn, N. et al. Prostaglandins Leukot Essent Fatty Acids. 2008 Apr-May;78(4-5):311-2 sin 6.

Johnson et al. 2009
75 children & adolescents over 6 months
Significant Improvement
  • Concentration and attention

Barragan-Perez, E.J., Heredia-Barragan, I., and Huerta-Albarran, R. 2011. 17(4): 148-153.

Richardson et al. 2005
117 children over 6 months
Significant Improvement

vs. placebo for measures reflecting:

  • Concentration and attention
  • Learning such as reading and
    spelling

Richardson, A.J. and Montgomery, Pediatrics. 2005 May;115(5):1360-6.

SFI Health Difference

EQUAZENTM with Equabalance ratio 9:3:1

There are now hundreds of formulations containing omega-3s or omega-6 as the main ingredients. So what makes EQUAZENTM with the specific ratio EPA:DHA:GLA = 9:3:1 different?

  • High quality with the optimal balance of EPA, DHA and GLA
  • Consistently reliable, batch after batch
  • Researched in clinical trials

That means, you can be confident that the EQUAZENTM product you are getting contains the same balance of ingredients that has been demonstrated in clinical research to support concentration, learning and reading. That’s the SFI Health difference.

EQUAZENTM: EPA:DHA:GLA = 9:3:1: A Summary

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Consistent quality

Through our rigorous processes, quality controls and extensive testing we help ensure that our clinically researched ratio 9:3:1 can provide the health outcomes demonstrated by clinical research

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Clinically researched ratio of fatty acids (EPA:DHA:GLA= 9:3:1)

Formulated to provide an optimal balance omega-3 and omega-6 essential fatty acids

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12 Clinical trials

EQUAZENTM clinical studies support its role in improving cognitive functions in healthy subjects6-11

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Recommended and used worldwide

to support healthy brain development

Our Source to Patient journey

We take great pride in our unique Omega-3 with Omega-6 food supplements and use only the best ingredients and pharmaceutical standard processing techniques, in order to maintain the high quality that our customers have come to expect over the years.

Follow the source to patient journey
References
  1. Johnson et al. Child Psychol Psychiatry. 2017 Jan;58(1):83-93.
  2. Parletta et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Aug;89(2-3):71-9.
  3. Bauer I. et al. Hum Psychopharmacol. 2014 Mar;29(2):133-44.
  4. Bauer I. et al. PLoS One. 2011;6(12):e28214.
  5. Assisi A. et al. Fish oil and mental health: the role of n-3 long chain polyunsaturated fatty acids in cognitive development and neurological disorders. International clinical pharmacology 2006,21:319-336
  6. EFSA Journal 2010;8(10):1796. DOI:10.2903/j.efsa.2010.1796
  7. Sinn, N. and Bryan, J Dev Behav Pediatr. 2007 Apr;28(2):82-91.
  8. Barragan-Perez, E.J., Heredia-Barragan, I., and Huerta-Albarran, R. 2011. 17(4): 148-153.
  9. Johnson, M. et al. J Atten Disord. 2009 Mar;12(5):394-401.
  10. Johnson, M. et al. J Atten Disord. 2012 Dec;4(4):199-204.
  11. Sinn, N. et al. Prostaglandins Leukot Essent Fatty Acids. 2008 Apr-May;78(4-5):311-2 sin 6.
  12. Barragán E, Breuer D, Döpfner M. J Atten Disord i-9. 2014.
  13. Richardson, A.J. and Montgomery, Pediatrics. 2005 May;115(5):1360-6.
  14. Milte et al. Nutrition. 2012 Jun;28(6):670-7.
  15. Wiktorowska-Owczarek A, Berezińska M, Nowak JZ. PUFAs: Structures, Metabolism and Functions. Adv Clin Exp Med. 2015 Nov-Dec;24(6):931-41. doi: 10.17219/acem/31243.
  16. Sergeant S, Rahbar E, Chilton FH. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86. doi: 10.1016/j.ejphar.2016.04.020.
  17. Bell JG, MacKinlay EE, Dick JR, MacDonald DJ, Boyle RM, Glen AC. Essential fatty acids and phospholipase A2 in autistic spectrum disorders. Prostaglandins Leukot Essent Fatty Acids. 2004 Oct;71(4):201-4.
  18. Bennett CN, Horrobin DF. Gene targets related to phospholipid and fatty acid metabolism in schizophrenia and other psychiatric disorders: an update. Prostaglandins Leukot Essent Fatty Acids. 2000 Jul-Aug;63(1-2):47-59.